Addenda to Newsletter18 ( Edited : April, 2002 )

LEAD

Lead is particularly toxic to the brain, kidneys, reproductive system, and cardiovascular system. Exposures can cause impairments in intellectual functioning, kidney damage, infertility, miscarriage, and hypertension. Lead is a special hazard for young children. Several studies have shown that lead exposures can significantly reduce the IQ of school-aged children; some estimates suggest that every 10-microgram-per-deciliter increase in lead levels in the blood is associated with a 1- to 5-point decrease in the IQ of exposed children [184]. Lead exposures have also been associated with aggressive behavior, delinquency, and attention disorders in boys between the ages of 7 and 11 In adults, lead exposure has been related to increased blood pressure and hypertension, conditions known to increase the risk of cardiovascular disease.

Occupational Safety and Health Administration. US Department of Labor (OSHA) More

Lead As An Essential Element

Lead was until now only considered as a poisonous heavy metal.
Lead could be upgraded to an essential element. A lead-dependent enzyme (the leadzyme) was discovered and described by Sugimoto N. Leadzyme is working with a lead ion (Pb2+) to regulate the transcription of genes. The transcription of a gene is like copying a blueprint (the gene) stored in the DNA of the chromosome to make the instructions it contains accessible for the biochemical machinery of our cells.